Kirsner炎症性肠疾病(第6版) Kirsner's Inflammatory Bowel Diseases 下载 pdf 百度网盘 epub 免费 2025 电子书 mobi 在线
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内容简介:
This comprehensive New Edition describes all of the latest scientific and clinical advances in the field of inflammatory bowel disease (IBD). A new editorial teamjoined by a superb group of international authoritiesexamine every aspect of IBDincluding etiology and pathogenesis, diagnosis and evaluation, medical and surgical therapy, and more. A wealth of expanded coverage, additional international contributors, extensive updating throughout, and numerous diagnostic and therapeutic algorithms make this an essential resource.
Emphasizes evidence-based medicine in the section on medical therapy.
Features a detailed de*ion of inflammatory and immunologic pathways, allowing the reader to fully understand the contributing influences to the inflammation of IBD.
Presents separate chapters on molecular genetics and clinical genetics for more in-depth coverage of each aspect of inflammatory bowel disease genetics.
Provides a comprehensive review of IBD through abundant, high-quality endoscopic, radiographic, and histologic photographsplacing the various diagnostic modalities in perspective.
Offers extensive coverage of postoperative recurrence of Crohn's disease
· pouchitis
· microscopic colitis
· perianal disease
· and osteoporosis.
Includes up-to-the-minute guidance (including many 2003 references).
Features a new editorial team, joined by numerous new contributors who provide fresh, global perspectives.
Includes nine new chapters.
Offers expanded coverage throughout, and through revisions of all pre-existing chapters.
With over 75 additional contributing experts.
书籍目录:
List of Contributors
Foreword
Preface
Section I Mucosal protection and homeostasis
1.Intestinal epithelia barrier function: characteristics and responses to neutrophil transepithelial migration
2.Epithelial restitution and intestinal repair
3.Epithelial-microbial interactions
4.Immune cell-epithelial cell interactions
5.The regulation of mucosal homeostasis and its relation to inflammatory bowel diseases
6.T-lymphocyte trafficking
7.Leukocyte, platelet and endothelial cell interactions in the inflammatory bowel diseases
Section II Etiology and pathogenesis
8.Genetics: molecular and chromosomal considerations
9.Animal models of intestinal inflammation
10.Microbial influences in inflammatory bowel diseases: role in pathogenesis and clinical implications
11.Mechanisms of tissue injury
12.Cytokines and inflammatory mediators
13.T-lymphocyte dysregulation
14.Neuroimmune interactions in the inflamed intestine
15.Fibrogenesis
16.Colorectal cancer in inflammatory bowel disease:molecular considerations
Section III Epidemiology, clinical features and natural history
17.Epidemiology of inflammatory bowel diseases
18.Clinical genetics of inflammatory bowel diseases:genetic epidemiology, genotype-phenotype correlations and pharmacogenetics
19.Clinical course and natural history of ulcerative colitis
20.Clinical features and natural history of Crohn's disease
21.Clinical features and natural history of pediatric inflammatory bowel diseases
22.Physiologic consequences of surgical treatment for inflammatory bowel disease
23.Fertility and pregnancy
24.Psychosocial factors in ulcerative colitis and Crohn's disease
Section IV Diagnosis and evaluation
Section V Medical therapy
Section VI Surgical therapy
Section VII Complications and associated diseases
Index
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